Newly Approved Alternative to Botox May be Superior
May 9, 2012 § Leave a comment
I know what you may be thinking, ‘Another wrinkle treatment to choose from?,’ but this should help to narrow down the selection. Recent research shows that Xeomin might actually be a better alternative to both of its cousins, Botox and Dysport.
This new alternative, sometimes called “the third Botox,” is produced by Merz Pharmaceuticals. Similar to Botox and Dysport, Xeomin is an injectable neuromuscular paralytic agent. It is used to treat conditions that are caused by muscle spasms, such as Cervical Dystonia, Blepharospasm, and Spacity. Cervical Dystonia is characterized by spastic twists of the head and neck to one side, whereas Blepharospasm is an uncontrollable twitching of the eyelids. Spacity pertains to the excessive contraction of the muscles.
Xeomin has also just recently been found to temporarily improve the appearance of moderate to severe wrinkles in adults. Just like Botox and Dysport, it is chiefly comprised of Botulinum Toxin A, with a slight variation (giving it the name incobotulinumtoxinA). B toxin A paralyzes facial muscles by preventing the exchange of nerve signals between the brain and the muscles. By restricting the movement of facial muscles, the wrinkling of the skin is avoided.
Only doctors notice the difference between Xeomin and Botox. This is because Xeomin is the only currently approved botulinum toxin that does not require refrigeration prior to its injection, which simplifies administration. This also means Xeomin is the most environmentally friendly Botox variety product on the market.
Xeomin is also unique because it lacks the accessory proteins contained in the two other main botulinum composites. This makes the results of Xeomin injections last longer because the lack of these additives reduce the risk of the immune system developing antibodies against the compound, antibodies that would eventually wear down the effects of B toxin A.
The injections only take about 30 minutes – just as long as a Botox injection – with minimal recovery time. Results should manifest within a week of the application, and usually last from three to up to six months.
It was only FDA approved for treating glabellar lines in July of 2011. Approval was based on the results of two crucial U.S. clinical trials involving 547 healthy adult patients and 16 investigational sites. Both trials yielded successful results, with Xeomin significantly improving the appearance of glabellar lines just 30 days after the first injection.
In terms of side effects, Xeomin entails the same risks as Botox and Dysport, only manifesting if the substance spreads to other areas of the body. When used medicinally, other possible side effects include neck pain, muscle weakness, injection site pain, musculoskeletal pain, eyelid sagging, dry eyes and/or mouth, diarrhea, headache, visual impairment, shortness of breath, and upper respiratory infections. Only about 1% of patients reported experiencing the preceding list, and these side effects differ depending on what the patient is being treated for.
Xeomin will be available to physicians nationwide in the spring of 2012. Further testing is required to decipher the benefits of using Xeomin in lieu of Botox of Dysport.
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