Perlane – The Natural Alternative

May 9, 2012 § Leave a comment

Just like other dermal fillers, Perlane works to restore facial surface contour. It is used to improve wrinkles, worry-lines, nasolabial folds, acne scars, cheek depressions, and other age-related imperfections. Doctors actually favor this product over others, especially for lip augmentation procedures, ultrafine line improvement, and scar treatment.


Perlane is made primarily of a biotechnologically engineered, non-immunogenic, stabilized hyaluronic acid gel. No animal products are used. It uses components that are naturally found in the skin and other tissues of the human body and, because of this, patients do not require an allergy test prior to using Perlane. Also, because Perlane infuses the skin with hyaluronic acid, it acts as a supplement to replenish the body’s naturally-depleting supply.

The filler is injected into the skin, much like other dermal fillers, and after a few hours a lift and added volume becomes visible in the area of injection. What makes Perlane unique is that it is comprised of smaller particles – three-dimensional hydrophilic molecules – that bind to water molecules as they degrade, which help cells maintain hydration and volume. This makes it better-suited for those with thinner and thus more sensitive skin.

Perlane differs from Botox in the type of injectable filler that is used. Perlane fills in the trouble areas with a plumping hyaluronic acid, which binds to muscles and tissues to make them fuller. It is a replenishing of a natural substance already found in the body. Botox uses Botulinum Toxin A to paralyze facial muscles, causing wrinkles to disappear because the paralysis limits further movement in the treated area. While Perlane is a dermal filler, Botox is not.

Another significant difference between these two products is that while the effects of Botox are permanent, Perlane injections are not. Although the results of Perlane treatments are only temporarily, as the natural substance biodegrades in the body after six to twelve months of injection, the product still lasts twice as long as a bovine-based collagen injection. Also, if results of a Perlane injection are undesirable, patients may rest assured that they will return to normal after the substance naturally biodegrades in the body. The effects of Botox, on the other hand, may permanently hinder an individual’s ability to make facial expressions, such as smiling.

Another product that is even more similar to Perlane is Restylane. Although manufactured by the same company, and are both comprised of hyaluronic acid, the two fillers differ in their intended usage. Restylane is best used for shallow areas, where Perlane is better for deep facial folds, such as around the lips and eyes. If Restylane is injected into deep wrinkles, it has little to no effect. Likewise, if Perlane is injected to shallow divets and lines, it has too much of a plumping effect, causing bumps and over-inflation. Also, Perlane’s effects last longer than Restylane because the particles in Perlane are designed to clump together, making them harder to metabolize.

Some side effects of Perlane are skin discoloration (bruising), swelling, redness, tenderness, pain, itching, or small lumps at the site of injection. The majority of these effects only last less than a week. Perlane carries the theoretical risk of infection, so patients are told to avoid injecting sites with sores, pimples, rashes, or other skin abrasions. Also, injection of Perlane may cause scar tissue, and in African-American patients this could result in hyperpigmentation.

Perlane was FDA approved in May of 2007 for implantation into the deep dermis to superficial subcutis. It should not be injected anywhere except the skin or just under the skin, and should only be administered under the supervision of a licensed practitioner.

You can purchase Perlane wholesale from Ace-medica.com for brand name quality products at the lowest prices!

Works Cited

“Perlane”. Cosmetic Surgery Today. February 15, 2012. http://www.cosmeticsurgerytoday.com/injectable-fillers/perlane/.

“Perlane”. Drugs.com. February 15, 2012. http://www.drugs.com/perlane.html.

“Perlane”. Healthy Skin Portal.com. Signature Forum. February 15, 2012.

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