May 14, 2012 § Leave a comment
Wrinkles are an inevitable occurrence. Unfortunately, they are also telltale signs of aging. But they do not have to be. The cosmetological industry has many options for those seeking a more youthful appearance from facelifts to Botox injections.
One such option, which surpasses Botox and many of its competitors, is the Radiesse filler. This product is still a very effective way to deal with wrinkles, but it is among the more natural and safer alternatives.
The product has been tested very thoroughly over the past few years. Radiesse has two FDA approvals and a number of FDA clearances. This is due to its biocompatible composition. It is made of substances that are almost identical to human bodily substances. This eliminates allergic reactions and reduces side effects.
The Radiesse dermal filler consists of calcium-based microspheres suspended in a water-based gel. This filler is injected into the skin in a way that is minimally invasive, evading harmful surgical procedures and long recovery times. The procedure is also very quick (administered in under an hour) and the results are instantaneous.
A unique feature of Radiesse is its continued work overtime. While most other products either lift or tighten for a terminable amount of time, Radiesse stimulates a process called collagenesis – the production and growth of new collagen – in the area of injection. This means that Radiesse helps the body to prevent future wrinkles while erasing existing ones. Results can last for up to a year. For this reason, younger patients can use it to prevent wrinkles while eliminating newly appearing wrinkles, slowing down the aging process.
“Radiesse”. Cosmetic Surgery Today. May 14, 2012. http://www.cosmeticsurgerytoday.com/injectable-fillers/radiesse/
May 9, 2012 § Leave a comment
I know what you may be thinking, ‘Another wrinkle treatment to choose from?,’ but this should help to narrow down the selection. Recent research shows that Xeomin might actually be a better alternative to both of its cousins, Botox and Dysport.
This new alternative, sometimes called “the third Botox,” is produced by Merz Pharmaceuticals. Similar to Botox and Dysport, Xeomin is an injectable neuromuscular paralytic agent. It is used to treat conditions that are caused by muscle spasms, such as Cervical Dystonia, Blepharospasm, and Spacity. Cervical Dystonia is characterized by spastic twists of the head and neck to one side, whereas Blepharospasm is an uncontrollable twitching of the eyelids. Spacity pertains to the excessive contraction of the muscles.
Xeomin has also just recently been found to temporarily improve the appearance of moderate to severe wrinkles in adults. Just like Botox and Dysport, it is chiefly comprised of Botulinum Toxin A, with a slight variation (giving it the name incobotulinumtoxinA). B toxin A paralyzes facial muscles by preventing the exchange of nerve signals between the brain and the muscles. By restricting the movement of facial muscles, the wrinkling of the skin is avoided.
Only doctors notice the difference between Xeomin and Botox. This is because Xeomin is the only currently approved botulinum toxin that does not require refrigeration prior to its injection, which simplifies administration. This also means Xeomin is the most environmentally friendly Botox variety product on the market.
Xeomin is also unique because it lacks the accessory proteins contained in the two other main botulinum composites. This makes the results of Xeomin injections last longer because the lack of these additives reduce the risk of the immune system developing antibodies against the compound, antibodies that would eventually wear down the effects of B toxin A.
The injections only take about 30 minutes – just as long as a Botox injection – with minimal recovery time. Results should manifest within a week of the application, and usually last from three to up to six months.
It was only FDA approved for treating glabellar lines in July of 2011. Approval was based on the results of two crucial U.S. clinical trials involving 547 healthy adult patients and 16 investigational sites. Both trials yielded successful results, with Xeomin significantly improving the appearance of glabellar lines just 30 days after the first injection.
In terms of side effects, Xeomin entails the same risks as Botox and Dysport, only manifesting if the substance spreads to other areas of the body. When used medicinally, other possible side effects include neck pain, muscle weakness, injection site pain, musculoskeletal pain, eyelid sagging, dry eyes and/or mouth, diarrhea, headache, visual impairment, shortness of breath, and upper respiratory infections. Only about 1% of patients reported experiencing the preceding list, and these side effects differ depending on what the patient is being treated for.
Xeomin will be available to physicians nationwide in the spring of 2012. Further testing is required to decipher the benefits of using Xeomin in lieu of Botox of Dysport.
You can purchase Xeomin wholesale from Ace-medica.com to get the brand name quality product at the lowest price available!
“Xeomin Injections What is Xeomin Treatment”. (July 25, 2009). Cheap Affordable Laser Liposuction. February 14, 2012. http://laserliposuctiontips.com/xeomin-injections-what-is-xeomin-treatment/.
“Xeomin”. C-Health. MediResource Inc. February 14, 2012. http://chealth.canoe.ca/drug_info_details.asp?brand_name_id=5557&rot=4.
“Merz Aesthetics Announces FDA Approval Of XEOMIN® (incobotulinumtoxinA) For The Temporary Improvement In The Appearance Of Moderate To Severe Glabellar Lines In Adult Patients”. (July 21, 2011). PR Newswire. February 14, 2011. http://www.prnewswire.com/news-releases/merz-aesthetics-announces-fda-approval-of-xeomin-incobotulinumtoxina-for-the-temporary-improvement-in-the-appearance-of-moderate-to-severe-glabellar-lines-in-adult-patients-125944538.html.
“Xeomin”. Cosmetic Surgery Today. February 14, 2012. http://www.cosmeticsurgerytoday.com/injectable-fillers/xeomin/.
May 3, 2012 § Leave a comment
Botox has long been the leading cosmetic procedure in the quest for a younger looking visage, but many veterans of this procedure lament the loss of their ability to express regular facial features. This diminished facial muscle strength is a result of the paralytic effect of the acetylcholine-blocking brotulinum toxins contained in Botox.
Reigning supreme as a more natural alternative to Botox is Juvéderm, an injectable dermal gel filler used to reduce facial wrinkles, plump thinning lips, add volume to sunken cheeks and cheekbones, and fill hollow spaces left by scars, especially those left by acne. It has even been used for aesthetic reasons in areas extraneous to the face, such as the knee. This is because, unlike Botox, it does not cause muscle paralysis.
Juvéderm is comprised mainly of hyaluronic acid (HA), which is a natural complex sugar found in the skin, muscles, and tendons of all living organisms. It retains water and thus hydrates the skin, resulting in a plumping effect. It gives the skin a smooth, natural look and feel.
The FDA approved Juvéderm in June of 2006 based on a double-blind, randomized and controlled clinical trial. 439 subjects of differing ethnicities were injected with the substance and followed for six months afterwards. They were injected with the Juvéderm in one nasolabial fold and Zyplast, a bovine-based collagen, in the other. Juvéderm proved more persistent in wrinkle correction. There was no hyperpigmentation or hypertrohpic scarring in the non-Caucasian patients. Also, 88% of subjects expressed a personal preference for Juvéderm.
One woman, a 39-year old newspaper employee with two daughters, expressed her delight with the success of the procedure. “The results look fabulous and made my lips large enough to wear brighter shades of lipstick without smearing any on my teeth,” she told CosmeticSurgery.com. “I didn’t want to look like Angelina Jolie; I just wanted fuller, natural-looking lips.”
Juvéderm differs from Botox in that it adds volume and elasticity to facial features, whereas Botox removes wrinkles and labial folds caused by repeated facial expressions. Unlike Botox, a synthetic material, hyaluronic acid is biodegradable and easily absorbed by the body over a period of approximately nine months. Also unlike Botox, because Juvéderm is made of natural materials, an allergy test is not required prior to receiving an injection. This eliminated preparation time for the treatment. Unfortunately this does mean that patients must undergo repeat injections in order maintain their youthful look, but it also means that undesired changes will fade away much quicker that a more permanent facial filler. “Permanent fillers can turn into permanent problems,” says Dr. Michael Coverman, M.D., board certified Austin dermatologist. “If you don’t like the changes, you must wait two years for the substance to dissolve.”
Juvéderm treatments are very short and noninvasive, with minimal recovery time required. Patients could receive the injections over their lunch break. Very rarely patients may experience redness or swelling in the treated area, but when these symptoms do occur, they disappear within days. An anesthetic is also not usually required, as it is for Botox. The Juvéderm gel has a smooth consistency, which helps to minimize the discomfort that sometimes occurs during the injection procedure of other dermal formulas.
You can purchase Juvéderm wholesale from Ace-medica.com to get the brand name quality product at the lowest price available.
“Juvederm”. (January 31, 2011). Drugs.com. February 12, 2012. http://www.drugs.com/juvederm.html.
“Juvederm Treatment”. (April 4, 2010). Articles Base. February 12, 2012. http://www.articlesbase.com/medicine-articles/juvederm-treatment-2098175.html.
“Chasing Botox: Juvederm”. (2012). CosmeticSurgery.com. February 12, 2012. http://www.cosmeticsurgery.com/articles/archive/an~226/.
March 31, 2012 § Leave a comment
Many ageing individuals long for that youthful glow of a wrinkle-free complexion. Advertisements for Botox® promise just that, and the customers are flocking. People are even hosting “Botox parties,” where men and women gather to sip cocktails and banish wrinkles together.
Despite the compound’s popularity, it was only approved by the U.S. Food and Drug Administration (FDA) for cosmetic use in 2002. This is because Botox is the trade name for a Botulinum Toxin A, a neurotoxin. In this sense, B. Toxin A is related to Botulism. Botulism is a serious form of food poisoning caused by eating preserved food that has been contaminated with Clostridium botulinum bacterium. Botulism causes paralysis.
Botulinum toxins block muscle-signaling neurons. They latch onto nerve endings, causing the suspension of acetylcholine – the neurotransmitter in charge of activating muscle contractions. This occurs when botulinum toxins attack a series of proteins – VAMP, Syntaxin, and SNAP-25 – that are necessary for the release of acetylcholine.
B. Toxin A is also used to treat conditions that involve involuntary spasmic muscle contractions, such as Cervical Dystonia, Strabismus, and Blepharospasm. Once the botulinum is injected into the muscle(s), muscles contractions are reduced or eliminated. Although the results are not permanent, they occur within a few hours to a few days after treatment, and last from three to eight months.
This is exactly why Botox injections work to correct and prevent wrinkles; if an area is paralyzed it cannot wrinkle. Injecting the toxin directly into a certain muscle greatly reduces the risk of it spreading to other areas of the body, such as the chest, where breathing can be impaired, causing death. This is why the Botox injections are localized to the face. The results of this facial treatment are also temporary, so repeat treatments are required – hence the indefatigable market for Botox.
Researchers are still investigating other uses for Botox. It has already been used to treat Hyperhidrosis. Investigation suggests that it may also benefit Spasmodic Dysphonia, a neurological disorder that affects the larynx.
Despite all of the purported benefits of Botox, the FDA has issued warnings of possible health hazards, specifically in the case of the aforementioned “Botox parties.” The FDA cautions that Botox injecting is a medical procedure that must be performed in a safe and controlled medical environment. Injecting an individual with any substance in the presence of alcohol is never a good idea, but imbibing alcohol at the time of an injection is likely to increase the bruising at the site of the injection. Individuals also need to be in a medical setting in order to ensure they are prepared for the possible risks and side effects.
Neer, Katherine. (August 24, 2001) “Botox: What You Need to Know”. HowStuffWorks.com. <http://health.howstuffworks.com/skin-care/beauty/skin-treatments/botox.htm> February 12, 2012